EU-OPENSCREEN ERIC is a non-profit research infrastructure, which operates on a global scale. We are funded by European countries (currently Czech Republic, Denmark, Finland, Latvia, Norway, Poland, Spain with Germany as host country) and offer access to academic high-throughput screening facilities and medicinal chemistry groups in these countries. Scientists from academia and industry can implement their screening projects at EU-OPENSCREEN´s partner laboratories using our general purpose diversity compound collection, the European Chemical Biology Library (ECBL), which is composed of 100.000 commercial compounds plus a growing number of compounds collected from academic chemistry groups. Hit optimisation can be done at our medicinal chemistry sites. All compounds will be profiled in a panel of about 20 assays, which will deliver extensive information on physico-chemical, cellular toxicity and anti-microbial properties.